AP52375PU-N KIR3DS1 (Center) antibody

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Rabbit anti Human KIR3DS1


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  • AP52375PU-N

Product Description for KIR3DS1

Rabbit anti Human KIR3DS1.
Properties: (Center)
Presentation: Aff - Purified
Product is tested for Flow Cytometry, Western blot / Immunoblot.

Properties for KIR3DS1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms 1, Killer cell immunoglobulin-like receptor, short cytoplasmic tail, three domains
Presentation Aff - Purified
Reactivity Hu
Applications F, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic peptide between 148-178 amino acids from the Central region of human KIR3DS1
Property Center
Add. information Molecular Weight: 42;447 Da

ELISA: 1/1000.
Western Blot: 1/100-1/500. 
Flow Cytometry: 1/10-1/50.

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Concentration 0.25 mg/ml
General Readings Zvyagin, I.V., et al. Cell. Mol. Immunol. 7(6):471-476(2010)
Jiao, Y.L., et al. J. Clin. Immunol. 30(6):840-844(2010)
Zhu, B.F., et al. Hum. Immunol. 71(11):1116-1123(2010)
Velickovic, M., et al. Tissue Antigens 76(4):325-330(2010)
Gao, X., et al. Clin. Immunol. 137(1):139-146(2010)

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Protein A column, followed by peptide affinity purification
Buffer System:
PBS containing 0.09% (W/V) Sodium Azide as preservative
Liquid purified Ig fraction
Aff - Purified
This antibody recognizes Human KIR3DS1 (Center).
Gene ID 3813

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