BB-PA1630 KLK5 antibody

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0.1 mg / €290.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Mouse, Rat KLK5

BB-PA1630

Product Description for KLK5

Rabbit anti Mouse, Rat KLK5.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for KLK5

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9D140
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminal of mouse KLK5, different from the related rat sequence by three amino acids.
GeneID:
68668
Background KLK5(Kallikrein-related peptidase 5), formerly known as stratum corneum tryptic enzyme (SCTE) or KLKL2, is a serine protease expressed in the epidermis. The KLK5 gene is one of the fifteen kallikrein subfamily members which is located on 19q13.41. KLK5 has been suggested to regulate cell shedding in conjunction with KLK7 and KLK14, given its ability to degrade proteins which form the extracellular component of cell junctions in the stratum corneum.The KLK5 gene contains 5 coding exons spanning 9.3. KLK5 expression is upregulated in a breast cancer cell line in the presence of estrogens and progestins and is associated with more aggressive forms of epithelial ovarian carcinoma.
General Readings
  1. Brattsand M, Egelrud T. Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation. J Biol Chem. 1999 Oct 15;274(42):30033-40. PubMed PMID: 10514489.
  2. Elliott MB, Irwin DM, Diamandis EP. In silico identification and Bayesian phylogenetic analysis of multiple new mammalian kallikrein gene families. Genomics. 2006 Nov;88(5):591-9. Epub 2006 Jul 7. PubMed PMID: 16829021.
  3. Gan L, Lee I, Smith R, Argonza-Barrett R, Lei H, McCuaig J, et al. Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. Gene. 2000 Oct 17;257(1):119-30. PubMed PMID: 11054574.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Format
Buffer System:
5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
State:
Lyophilized
Aff - Purified
Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

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