AP33374SU-N L-Kynurenic Acid antibody

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0.1 ml / €450.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti L-Kynurenic Acid

AP33374SU-N

Product Description for L-Kynurenic Acid

Rabbit anti L-Kynurenic Acid.
Presentation: Serum
Product is tested for Enzyme Immunoassay.

Properties for L-Kynurenic Acid

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms 4-hydroxyquinoline-2-carboxylic acid, KynA, kinurenic acid, kynuronic acid, quinurenic acid, transtorine
Presentation Serum
Applications E
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
L-Kynurenic Acid KLH-conjugated
Add. information CAS numbe: 492-27-3 
Molecular formula: C10H7NO3
Molar mass: 189.168 g/mol
Melting point: 282.5°C
Application ELISA: 1/8000.
Background Kynurenic acid (KYNA or KYN) is a product of the normal metabolism of amino acid L-tryptophan. It has been shown that kynurenic acid possesses neuroactive activity. It acts as an antiexcitotoxic and anticonvulsant, most likely through acting as an antagonist at excitatory amino acid receptors. Because of this activity, it may influence important neurophysiological and neuropathological processes. As a result, kynurenic acid has been considered for use in therapy in certain neurobiological disorders. Conversely, increased levels of kynurenic acid have also been linked to certain pathological conditions.
Kynurenic acid was discovered in 1853 by the German chemist Justus von Liebig in dog urine, which it was apparently named after. (1) 
It is formed from L-kynurenine in a reaction catalyzed by the enzyme kynurenine—oxoglutarate transaminase.
General Readings
  1. Liebig, J., Uber Kynurensäure, Justus Liebigs Ann. Chem., 86: 125-126, 1853.
Storage Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month 
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Lyophilized Serum
Serum
Reconstitution:
Restore in aqua bidest to initial volume
Specificity
Specificity:
This antibody detects L-Kynurenic acid. 
Cross reactivity obtained with 3-Hydroxy-Kynurenine, was less than 0.2%. 
Thre was no no cross reactivity obtained with Indole Serotonin, or Quinoline.

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