discontinued

GTX20780 Lambda light chain antibody

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0.5 ml / €330.00

Quick Overview

Mouse anti Human Lambda light chain N10/2

GTX20780

Product Description for Lambda light chain

Mouse anti Human Lambda light chain N10/2.
Presentation: Supernatant
Product is tested for Frozen Sections, Paraffin Sections.

Properties for Lambda light chain

Product Category Primary Antibodies
Quantity 0.5 ml
Presentation Supernatant
Reactivity Hu
Applications C, P
Clonality Monoclonal
Clone N10/2
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Purified IgG from human serum.
Application IHC-Fr, IHC-P
Background All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
Storage Keep as concentrated solution, aliquot and store at 4
Format
Purification:
Tissue culture supernatant
Buffer System:
Tissue culture supernatant with sodium azide
Purity:
Tissue culture supernatant
State:
Liquid
Supernatant
Specificity
Specificity:
Human - Not yet tested in other species

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