discontinued

NB100-62714 Lambda light chain antibody

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1 ml / €500.00

Quick Overview

Sheep anti Human Lambda light chain

NB100-62714

Product Description for Lambda light chain

Sheep anti Human Lambda light chain.
Presentation: AP
Product is tested for Enzyme Immunoassay.

Properties for Lambda light chain

Product Category Primary Antibodies
Quantity 1 ml
Presentation AP
Reactivity Hu
Applications E
Clonality Polyclonal
Host Sheep
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Made to Human LAMBDA LIGHT CHAIN
Application ELISA, This antibody is useful for ELISA, ELISA
Background All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Label:
Alkaline Phosphatase
AP
Buffer System:
Sodium Azide
Specificity
Specificity:
LAMBDA LIGHT CHAIN
Species:
Human

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