discontinued

AP33384SU-N Laminin antibody

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0.25 ml / €250.00

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Rabbit anti Human, Mouse Laminin

AP33384SU-N

Product Description for Laminin

Rabbit anti Human, Mouse Laminin.
Presentation: Serum
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Frozen Sections.

Properties for Laminin

Product Category Primary Antibodies
Quantity 0.25 ml
Presentation Serum
Reactivity Hu, Ms
Applications C, ICC/IF, P
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Laminin isolated from Engelbrecht-Holm-Swarm (EHS)-Mouse sarcoma.
Application Immunocytochemistry.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Paraffin Sections.
Working Dilutions: 1/50-1/500.
Background Laminin is a glycoprotein (Mr 850 - 1.000 kD, consisting of 3 glycosylated polypeptide chains with molecular weights of 440 and 225 (2x) kD) produced by various human epithelial and mesenchymal cells, and forms an extracellular matrix of thin filaments. In normal tissues, laminin is invariably present in all basal laminas surrounding muscle, nerve, fat and decidua cells and separates epithelial and endothelial cells from abutting connective tissues. Laminin has also been identified within the cytoplasm of breast epithelia, stromal cells of the endometrium, and within endothelial, bile duct epithelial and mesenchymal cells of the liver. Laminin has been found to be involved in cellular activities such as adhesion, spreading, differentiation, polarization, proliferation, locomotion, tissue invasion and chemotactic responses. 
Laminin has been shown to play a roll in cell adhesion and attachment in vivo and in vitro.
General Readings
  1. Christensen L. The distribution of fibronectin, laminin and tetranectin in human breast cancer with special attention to the extracellular matrix. APMIS Suppl. 1992;26:1-39. PubMed PMID: 1576006.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: One year from despatch.
Format
Preservatives:
0.09% Sodium Azide
State:
Liquid Serum
Serum
Species Reactivity
Species reactivity (tested):
Human, Mouse
Specificity
Specificity:
This antibody detects Laminin.
No cross reaction was obtained with Human type I, III, IV and V Collagen in Immunoblotting, whereas the antibody reacted with a distinct band of ~200-220 kD from a 8M Urea extract from amnion basement membrane.

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