bs-4700R Latent membrane protein 2 / LMP2 antibody

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0.1 ml / €240.00

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Rabbit anti Virus Latent membrane protein 2 / LMP2


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  • bs-4700R

Product Description for Latent membrane protein 2 / LMP2

Rabbit anti Virus Latent membrane protein 2 / LMP2.
Presentation: Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for Latent membrane protein 2 / LMP2

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms Latent membrane protein 2
Presentation Purified
Reactivity Vi
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Swiss Prot Num:
KLH conjugated synthetic peptide derived from HHV4t2 LMP2A.
Background Epstein Barr virus (EBV) is a member of the herpesvirus family and one of the most common human viruses. Most people become infected with EBV during their lives. Primary infections usually results in infectious mononucleosis (glandular fever) but the virus can also lay dormant in B lymphocytes and when reactivated become associated with more serious disease such as Burkitt's lymphoma, nasopharyngeal carcinoma and Hodgkin's disease. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals.
Storage Store at -20°C for 12 months.
Purified by Protein A and peptide affinity chromatography.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.

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