discontinued

AM00313PU-N Leukotriene C4 / E4 / D4 antibody

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0.1 mg / €320.00

Quick Overview

Rat anti Human Leukotriene C4 / E4 / D4 6E7

AM00313PU-N

Product Description for Leukotriene C4 / E4 / D4

Rat anti Human Leukotriene C4 / E4 / D4 6E7.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Radioimmunoassay.

Properties for Leukotriene C4 / E4 / D4

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms DM3121
Presentation Purified
Reactivity Hu
Applications E, R
Clonality Monoclonal
Clone 6E7
Host Rat
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Leukotriene C4
Application ELISA (for coating, order Ab without BSA).
Radioimmunoassay (RIA).
Recommended positive control: Breast Carcinoma.
Background Leukotrienes are newly formed mediators derived from arachidonic acid that is released from membrane phospholipids upon stimulation of phospholipases. As a result of their various paracrine effects, these mediators-among which the most important are leukotrienes B4, C4, D4, and E4 (LTB4, LTC4, LTD4, and LTE4) are likely to play a central role in bronchial obstruction in asthma. LTC4 and LTD4 act on all three effectors of bronchial obstruction, namely bronchial smooth muscle, vessels, and mucus secretory cells, whereas LTB4 is a potent chemotactic factor recruiting neutrophils, and to a lesser extent, eosinophils. Increased production of leukotrienes implies that they are directly involved in asthma.
Concentration 0.2 mg/ml
General Readings
  1. Munoz N M, et al. (1999) Am J Physiol, 277(4Pt1):L802-810
  2. Maclouf J, et al. (1996) Haemostasis Suppl, 4:28-36.
  3. Shimizu T et al. (1990) Adv Prostaglandin Thromboxane Leukot Res, 20:46-53.
Storage Store the antibody at 2 - 8 °C for one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G chromatography
Buffer System:
10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide.
State:
Liquid ascites fluid
Purified
Specificity
Specificity:
This antibody detects Leukotriene C4 / E4 / D4.

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