AM00313PU-N Leukotriene C4 / E4 / D4 antibody

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Rat anti Human Leukotriene C4 / E4 / D4 6E7


Product Description for Leukotriene C4 / E4 / D4

Rat anti Human Leukotriene C4 / E4 / D4 6E7.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Radioimmunoassay.

Properties for Leukotriene C4 / E4 / D4

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms DM3121
Presentation Purified
Reactivity Hu
Applications E, R
Clonality Monoclonal
Clone 6E7
Host Rat
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Leukotriene C4
Isotype control SM25P, SM25PX
Application ELISA (for coating, order Ab without BSA).
Radioimmunoassay (RIA).
Recommended positive control: Breast Carcinoma.
Background Leukotrienes are newly formed mediators derived from arachidonic acid that is released from membrane phospholipids upon stimulation of phospholipases. As a result of their various paracrine effects, these mediators-among which the most important are leukotrienes B4, C4, D4, and E4 (LTB4, LTC4, LTD4, and LTE4) are likely to play a central role in bronchial obstruction in asthma. LTC4 and LTD4 act on all three effectors of bronchial obstruction, namely bronchial smooth muscle, vessels, and mucus secretory cells, whereas LTB4 is a potent chemotactic factor recruiting neutrophils, and to a lesser extent, eosinophils. Increased production of leukotrienes implies that they are directly involved in asthma.
Concentration 0.2 mg/ml
General Readings
  1. Munoz N M, et al. (1999) Am J Physiol, 277(4Pt1):L802-810
  2. Maclouf J, et al. (1996) Haemostasis Suppl, 4:28-36.
  3. Shimizu T et al. (1990) Adv Prostaglandin Thromboxane Leukot Res, 20:46-53.
Storage Store the antibody at 2 - 8 °C for one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein G chromatography
Buffer System:
10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide.
Liquid ascites fluid
This antibody detects Leukotriene C4 / E4 / D4.

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