discontinued

AM32119LE-N Lipoteichic Acid (LTA) antibody

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0.2 mg / €620.00

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Mouse anti Lipoteichic Acid (LTA) 55

AM32119LE-N

Product Description for Lipoteichic Acid (LTA)

Mouse anti Lipoteichic Acid (LTA) 55.
Presentation: Low Endotoxin
Product is tested for Western blot / Immunoblot, Enzyme Immunoassay, Frozen Sections.

Properties for Lipoteichic Acid (LTA)

Product Category Primary Antibodies
Quantity 0.2 mg
Presentation Low Endotoxin
Applications C, E, WB
Clonality Monoclonal
Clone 55
Host Mouse
Isotype IgG3
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isotype control AM08210LE-N
Application Western blotting: Use 1/50 as starting working dilution.
Immunoassays
Immunohistochemistry on Frozen Sections: Use 1/50 as starting working dilution.
Background Lipoteichoic Acid is the major proinflammatory structure present within the cell wall layer of most gram-positive bacteria. It plays an important role in the initiation and progression of bacterial infection, inflammation, and septic shock. It induces several cytokines in vivo, and Lipoteichoic Acid and peptidoglycan (PepG) synergize to cause the induction of nitric oxide formation which can lead to multiple organ failure. Since Lipoteichoic Acid is also found in the cell walls of non-pathogenic gram-positive bacteria, it has been suggested that its structure and its ability to synergize with PepG determine the ability of a particular bacterium to cause septic shock.
Concentration > 0.2 mg/ml
General Readings
  1. van Langevelde P, van Dissel JT, Ravensbergen E, Appelmelk BJ, Schrijver IA, Groeneveld PH. Antibiotic-induced release of lipoteichoic acid and peptidoglycan from Staphylococcus aureus: quantitative measurements and biological reactivities. Antimicrob Agents Chemother. 1998 Dec;42(12):3073-8. PubMed PMID: 9835493. (Free PMC Article available, 5 images available)
  2. van Langevelde P, Ravensbergen E, Grashoff P, Beekhuizen H, Groeneveld PH, van Dissel JT. Antibiotic-induced cell wall fragments of Staphylococcus aureus increase endothelial chemokine secretion and adhesiveness for granulocytes. Antimicrob Agents Chemother. 1999 Dec;43(12):2984-9. PubMed PMID: 10582893. (Free PMC Article available, 4 images available)
  3. Henneke P, Morath S, Uematsu S, Weichert S, Pfitzenmaier M, Takeuchi O, et al. Role of lipoteichoic acid in the phagocyte response to group B streptococcus. J Immunol. 2005 May 15;174(10):6449-55. PubMed PMID: 15879147.
  4. Triantafilou M, Manukyan M, Mackie A, Morath S, Hartung T, Heine H, et al. Lipoteichoic acid and toll-like receptor 2 internalization and targeting to the Golgi are lipid raft-dependent. J Biol Chem. 2004 Sep 24;279(39):40882-9. Epub 2004 Jul 9. PubMed PMID: 15247273.
Storage Store the antibody undiluted at 2-8°C.
Shelf life: one year from despatch.
Format
Preservatives:
0.02% Sodium Azide
State:
Culture Medium with a Low Endotoxin Level
Low Endotoxin
Specificity
Specificity:
This Monoclonal antibody clone 55 reacts with Lipoteichoic Acid (LTA).

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