15711 Lipoteichoic Acid (LTA) antibody

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Mouse anti Lipoteichoic Acid (LTA)


Product Description for Lipoteichoic Acid (LTA)

Mouse anti Lipoteichoic Acid (LTA).
Presentation: Azide Free
Product is tested for Enzyme Immunoassay.

Properties for Lipoteichoic Acid (LTA)

Product Category Primary Antibodies
Quantity 0.5 mg
Presentation Azide Free
Applications E
Clonality Monoclonal
Host Mouse
Isotype IgG1
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer QED Bioscience Inc.

Datasheet Extract

Staphylococcus epidermidis, Hay strain (ATCC #55133).
Application ELISA: use at 0.1-1.0 ug/ml (optimized for LTA on solid phase).
Opsonization assay: use at 80-160 ug/ml (optimized for Staph. epidermidis, Hay strain). 
Dilute in PBS or medium which is identical to that used in the assay system.
Background Lipoteichoic acid (LTA) is the major proinflammatory structure present within the cell wall layer of most gram-positive bacteria. It plays an important role in the initiation and progression of bacterial infection, inflammation, and septic shock. LTA induces several cytokines in vivo, and LTA and peptidoglycan (PepG) synergize to cause the induction of nitric oxide formation which can lead to multiple organ failure. Since LTA is also found in the cell walls of non-pathogenic gram-positive bacteria, it has been suggested that the structure of LTA , and its ability to synergize with PepG, determines the ability of a particular bacterium to cause septic shock.
Storage This antibody is stable for at least one (1) year at -20°C.
Avoid multiple freeze-thaw cycles.
Buffer System:
PBS, pH 7.4
Protein G-purified antibody
Azide Free
This antibody reacts with lipoteichoic acid of Staph epidermidis, Hay strain, as well as clinical strains of Staph. epidermidis (types I, II, and III), Staph. aureus strains 5 and 8, Strep. pyogenes, Strep. fecaelis, and Strep. mutans. It does not react with peptidoglycan of Staph. aureus or peptidoglycanrhamnose, nor does it react with pneumococcal polysaccharides.
This antibody does not cross-react with E. coli or H. influenzae type B.

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