NB100-94261 Livin antibody

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Rabbit anti Human Livin

Product Description for Livin

Rabbit anti Human Livin.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for Livin

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity Hu
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Rabbit anti-Livin polyclonal antibody was raised with a synthetic peptide (CRAPVRSRVRTFLS) corresponding to amino acids 264 to 280 of the short form and 281 to 298 of the long form of human Livin (1,3). This sequence is identical between alpha and beta forms of the Livin proteins.
Add. information Research Areas: DNA Repair
Application Western Blot, This antibody can be used for detection of Livin by Western blot at 2 to 4 ug/ml. Human Raji cell lysate can be used as a positive control and a band at 33 kDa can be detected. A lower but much weaker band at 30 kDa was detected in Raji cell lysate, which may represent the short form of Livin., Western Blot 2-4 ug/ml,
Background Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel member in the IAP protein family was recently identified and designated Livin and KIAP for kidney IAP (1,2). Livin/XIAP contains a single baculoviral IAP repeat (BIR) domain and a RING finger domain and has two isoforms termed Livin-alpha and Livin-beta (1,3). Transfection of Livin in cells resulted in protection from apoptosis induced by FADD, BAX, RIP, RIP3 and DR6 (1). Livin has direct interaction with several caspases including caspase-3, -7, and
Storage Store at 4C. Do not freeze.
IgG purified
Buffer System:
0.02% Sodium Azide
IgG purified
Livin, KIAP

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