discontinued

GTX45319 LMX1A antibody

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50 µg / €330.00

Quick Overview

Rabbit anti Human LMX1A

GTX45319

Product Description for LMX1A

Rabbit anti Human LMX1A.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for LMX1A

Product Category Primary Antibodies
Quantity 50 µg
Presentation Aff - Purified
Reactivity Hu
Applications P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide derived from a region between residues 244-293 of human LMX1A.
Application IHC-P, WB
Background Lmx1a (LIM homeodomain transcription factor) controls multiple aspects of dorsal midline patterning and is a major mediator of early Bmp signaling in the developing spinal cord. Lmx1a acts to withdraw dorsal spinal cord progenitors from the cell cycle and simultaneously direct their differentiation into functional roof plate cells. Furthermore, Lmx1a is critical along with Msx1 as an intrinsic dopamine-neuron determinant. An early activity of Lmx1a is to induce the expression of Msx1, which complements Lmx1a by inducing the proneural protein Ngn2 and neuronal differentiation. Expression of Lmx1a in embryonic stem cells results in a robust generation of dopamine neurons with a "correct" midbrain identity.
Concentration 1 mg/ml
Storage Keep as concentrated solution. Store at 4
Format
Purification:
Immunogen affinity purified
Buffer System:
Preservative: NoneConstituents: 2% Sucrose, PBS
Purity:
Immunogen affinity purified
State:
Liquid
Aff - Purified
Specificity
Specificity:
Reacts with Human.Not yet tested in other species.

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