NB100-56847 LOXL2 antibody

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Rabbit anti Human, Monkey LOXL2


Product Description for LOXL2

Rabbit anti Human, Monkey LOXL2.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay.

Properties for LOXL2

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Hu, Mky
Applications E
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Background Principal Names: LOXL2; Lysyl oxidase-like protein 2; Lysyl oxidase related protein 2; WS9-14; LOR2; ENTPD4; NTPDase 4; LAP70; LALP70; Official Gene Symbol: LOXL2 Gene ID: 4017 (human) Gene Map Locus: 8p21.3-p21.2 (Human) Lysyl Oxidase (LO) is an extracellular, copper-dependent enzyme that initiates the cross-linking of collagens and elastin by catalyzing the oxidative deamination of peptidyl lysine to alpha-aminoadipic-delta-semialdehyde. Members of LO family have diverse functions which include tumor suppression and cell adhesion and senescence. LOXL2, a 87KDa protein, is a novel member of this family. It contains 3 potential N-linked glycosylation sites, 4 scavenger receptor cysteine-rich (SRCR) domains and highly conserved copper-binding and Lysyl-tyrosylquinone cofactor sites. It is a component of extracellular matrix that might be involved in cell adhesion and senescence. Role of LOXL2 has been implicated in malignant transformation.
Affinity Purified
Buffer System:
PBS containing 0.2% gelatin and 0.05% sodium azide. Sodium azide is highly toxic.
Affinity Purified
Aff - Purified
Human, Chimpanzee, Dog, Bovine Not yet tested in other species.

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