GTX22572 LRP5 + LRP6 antibody

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50 µg / €350.00

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Mouse anti Human, Mouse LRP5 + LRP6 1A12


Product Description for LRP5 + LRP6

Mouse anti Human, Mouse LRP5 + LRP6 1A12.
Presentation: Ig Fraction
Product is tested for Western blot / Immunoblot.

Properties for LRP5 + LRP6

Product Category Primary Antibodies
Quantity 50 µg
Synonyms LRP5, LRP6, LRP7, Low-density lipoprotein receptor-related protein 5, Low-density lipoprotein receptor-related protein 6
Presentation Ig Fraction
Reactivity Hu, Ms
Applications WB
Clonality Monoclonal
Clone 1A12
Host Mouse
Isotype IgG2b
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic peptide: DTGTDRIEVTR (Human).These residues are completely conserved between human and mouse; and between LRP 5 and LRP 6.
Application WB
Background LDL related proteins, LRP 5 and LRP 6, are members of the LDL receptor superfamily, which were found to be involved in the canonical Wnt signaling pathway. Mammalian LRP 6 was shown to bind to Wnt 1 and enhance Wnt-induced developmental processes in Xenopus embryos. Mice lacking LRP 6 exhibited developmental defects that are similar to those caused by deficiencies in various Wnt proteins. Recent work also shows that Wnt proteins induce the binding of LRP 5 to Axin, leading Axin degradation and beta catenin stabilization.
Concentration 1 mg/ml
Storage Keep as concentrated solution. Store at 4
IgG fraction
Buffer System:
Preservative: 0.01% Sodium Azide; Constituents: 25% Glycerol, 0.5% BSA, 0.15M Sodium Chloride, 10mM Tris-glycine. pH 7
IgG fraction
Ig Fraction
Cross-reacts with Human and Mouse. Not yet tested in other species.

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