AM50011PU-N LSM2 antibody

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0.1 ml / €310.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Human LSM2 AT2B2

Product Description for LSM2

Mouse anti Human LSM2 AT2B2.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Western blot / Immunoblot.

Properties for LSM2

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms C6orf28, G7B, Small nuclear ribonuclear protein D homolog, U6 snRNA-associated Sm-like protein LSm2, snRNP core Sm-like protein Sm-x5
Presentation Purified
Reactivity Hu
Applications E, WB
Clonality Monoclonal
Clone AT2B2
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9Y333
Immunogen:
Recombinant human LSm2 (1-95aa) purified from E. coli
GeneID:
57819
Isotype control AM03096PU-N
Application The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000~1:3,000.
Background LSM2 is a member of the LSm family of RNA-binding proteins. Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner. Component of the cytoplasmic complex which is thought to be involved in mRNA degradation by activating the decapping step. Component of the nuclear LSM2 complex, which is involved in splicing of nuclear mRNAs. LSM2 associates with multiple snRNP complexes containing the U6 snRNA It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. It probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping. LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA. LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
Concentration 1.0 mg/ml
General Readings Luhtala N, Parker R.Nucleic Acids Res. 2009 Sep;37(16):5529-36.Fernandez CF, Pannone BK, Chen X, Fuchs G, Wolin SL .Mol Biol Cell. 2004Jun;15(6):2842-52. Achsel T., et al. (1999) EMBO J. 18:5789-5802
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein-G affinity chromatography
Buffer System:
PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State:
Liquid purified Ig fraction
Purified
Specificity
Species:
Human

Accessory Products

Proteins and/or Positive Controls

Proteins for LSM2 (5 products)

Catalog No. Species Pres. Purity   Source  

LSM2 (1-95, His-tag)

LSM2 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

LSM2 (1-95, His-tag)

LSM2 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

LSM2

LSM2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

LSM2

LSM2 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

LSM2

LSM2 Human
  Abnova Taiwan Corp.

Positive controls for LSM2 (2 products)

Catalog No. Species Pres. Purity   Source  

LSM2 Lysate

Western Blot: LSM2 Lysate [NBL1-12725] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for LSM2.
  Novus Biologicals Inc.

LSM2 overexpression lysate

LSM2 overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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