BM5544 Lung Cancer Marker MOC-21 antibody

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Mouse anti Human Lung Cancer Marker MOC-21 MOC-21


Product Description for Lung Cancer Marker MOC-21

Mouse anti Human Lung Cancer Marker MOC-21 MOC-21.
Presentation: Supernatant
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Lung Cancer Marker MOC-21

Product Category Primary Antibodies
Quantity 1 ml
Presentation Supernatant
Reactivity Hu
Applications C, ICC/IF, WB
Clonality Monoclonal
Clone MOC-21
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isolated from small cell lung carcinoma-derived cell line.
Application Immunohistochemistry on frozen sections: 1:5 - 1:10; 1 h at room temperature.
Recommended for Positive Control: Brain/adrenal gland.
Cell suspensions.
General Readings
  1. Berendsen HH, de Leij L, Postmus PE, Ter Haar JG, Poppema S, The TH. Detection of small cell lung cancer metastases in bone marrow aspirates using monoclonal antibody directed against neuroendocrine differentiation antigen. J Clin Pathol. 1988 Mar;41(3):273-6. PubMed PMID: 2834417. (Free PMC Article available)
  2. Berendsen HH, De Leij L, Poppema S, Postmus PE, Sluiter HJ, The H. Simultaneous standard light microscopy and immunohistology on bronchoscopically procured lung cancer specimens. Eur J Cancer Clin Oncol. 1988 May;24(5):915-21. PubMed PMID: 2844544.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
PBS with 1% BSA and 0.1% Na-Azide
Liquid Culture supernatant
MOC-21 reacts with membrane-associated proteins of 120 kD, 125 kD and 145 kD in normal and malignant tis-sue, including a subgroup of SCLC. Lack of reactivity with MOC-21 and MOC-32 (Cat. No. BM5545) within this SCLC subgroup correlates with a bad response to che-motherapy. Special procedure for bronchoscopically pro-cured material (see ref. 2).

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