AM08064BT-N Ly49C/F/H/I antibody

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0.5 mg / €350.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

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Hamster anti Mouse Ly49C/F/H/I 14B11

AM08064BT-N

Product Description for Ly49C/F/H/I

Hamster anti Mouse Ly49C/F/H/I 14B11.
Presentation: Biotin
Product is tested for Flow Cytometry.

Properties for Ly49C/F/H/I

Product Category Primary Antibodies
Target Category
Quantity 0.5 mg
Synonyms Killer cell lectin-like receptor, Klra3, Klra6, Klra8, Klra9, Ly-49C, Ly-49F, Ly-49H, Ly-49I, Ly49C, Ly49F, Ly49H, Ly49I, T cell surface glycoprotein Ly 49C, T cell surface glycoprotein Ly 49F, T cell surface glycoprotein Ly 49H, T cell surface glycoprotein Ly 49I
Presentation Biotin
Reactivity Ms
Applications F
Clonality Monoclonal
Clone 14B11
Host Hamster
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q64329
GeneID:
16634
Application Flow Cytometry: < / = 1 µg/10e6 cells. (Ref.1,3)
Background Ly49C, Ly49F, Ly49H and Ly49I are members of the lectin like homodimeric Ly49 family of cell surface receptors. Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down regulated. (Ref.2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells.
Concentration 0.5 mg/ml
General Readings
  1. Coles, M.C., C.W. McMahon, H. Takizawa, and D.H. Raulet. 2000. Memory Eur. J. Immunol. 30:236.
  2. Ljunggren, H.G., and K. Karre. 1990. Immunol. Today 11:237.
  3. McMahon, C., and D.H. Raulet. Personal communication.
Storage Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
Biotin
Buffer System:
PBS containing 0.09% Sodium Azide as preservative.
State:
Liquid purified Ig fraction.
Specificity
Specificity:
This antibody is specific to an epitope common to the Ly49C, Ly49F, Ly49H and Ly49I allelic/splice variants.
The antibody stains ~ 90% of NK1.1+CD3- splenocytes, and ~ 6% of CD8+ spleen cells from C57BL/6 mice. (Ref.1) The antibody also stains 30-80% of NK1.1+CD3-splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J).
Species:
Mouse.
Gene ID 16640

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