BB-PA1327 Ly6a antibody

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Regular Price: 0.1 mg / €290.00

Special Price: 0.1 mg / €182.00

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Quick Overview

Rabbit anti Rat Ly6a

BB-PA1327

Product Description for Ly6a

Rabbit anti Rat Ly6a.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Ly6a

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Immunogen
Swiss Prot Num:
D3ZPQ1
Immunogen:
A synthetic peptide corresponding to a sequence of rat Ly6a.
GeneID:
362935
Background SCA1(Stem cell antigen-1), also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is a glycosylphosphotidylinositol-anchored protein that identifies many tissue progenitor cells. Epting CL et al identified Sca-1 as a marker of myogenic precursor cells and subsequently demonstrated that Sca-1 regulates proliferation of activated myoblasts, suggesting an important role for Sca-1 in skeletal muscle homeostasis. And Bradfute SB et al experimental data indicate that Sca-1 plays a role in hematopoietic progenitor/stem cell lineage fate and c-kit expression. In addition, mouse Sca-1 overexpression affects human as well as mouse stem/progenitor cell activity, suggesting the possibility of a functional human Sca-1 homologue.
General Readings
  1. Epting CL, King FW, Pedersen A, Zaman J, Ritner C, Bernstein HS. Stem cell antigen-1 localizes to lipid microdomains and associates with insulin degrading enzyme in skeletal myoblasts. J Cell Physiol. 2008 Oct;217(1):250-60. doi: 10.1002/jcp.21500. PubMed PMID: 18506847. (Free PMC Article available, 6 images available)
  2. Bradfute SB, Graubert TA, Goodell MA. Roles of Sca-1 in hematopoietic stem/progenitor cell function. Exp Hematol. 2005 Jul;33(7):836-43. PubMed PMID: 15963860.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Format
Buffer System:
5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
State:
Lyophilized
Aff - Purified
Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

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