BB-PA1327 Ly6a antibody

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Regular Price: 0.1 mg / €290.00

Special Price: 0.1 mg / €182.00

Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Rat Ly6a


Product Description for Ly6a

Rabbit anti Rat Ly6a.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for Ly6a

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Aff - Purified
Reactivity Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Boster Immunoleader
Manufacturer certificates ISO 9001

Datasheet Extract

Swiss Prot Num:
A synthetic peptide corresponding to a sequence of rat Ly6a.
Background SCA1(Stem cell antigen-1), also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is a glycosylphosphotidylinositol-anchored protein that identifies many tissue progenitor cells. Epting CL et al identified Sca-1 as a marker of myogenic precursor cells and subsequently demonstrated that Sca-1 regulates proliferation of activated myoblasts, suggesting an important role for Sca-1 in skeletal muscle homeostasis. And Bradfute SB et al experimental data indicate that Sca-1 plays a role in hematopoietic progenitor/stem cell lineage fate and c-kit expression. In addition, mouse Sca-1 overexpression affects human as well as mouse stem/progenitor cell activity, suggesting the possibility of a functional human Sca-1 homologue.
General Readings
  1. Epting CL, King FW, Pedersen A, Zaman J, Ritner C, Bernstein HS. Stem cell antigen-1 localizes to lipid microdomains and associates with insulin degrading enzyme in skeletal myoblasts. J Cell Physiol. 2008 Oct;217(1):250-60. doi: 10.1002/jcp.21500. PubMed PMID: 18506847. (Free PMC Article available, 6 images available)
  2. Bradfute SB, Graubert TA, Goodell MA. Roles of Sca-1 in hematopoietic stem/progenitor cell function. Exp Hematol. 2005 Jul;33(7):836-43. PubMed PMID: 15963860.
Storage At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Buffer System:
5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Aff - Purified
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

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