discontinued

TA352685 Ly6A/E / SCA1 antibody

Rat Monoclonal anti-Ly-6A/E (Sca-1) Antibody

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Rat anti Mouse Ly6A/E / SCA1 D7

Product Description for Ly6A/E / SCA1

Rat anti Mouse Ly6A/E / SCA1 D7.
Presentation: Purified
Product is tested for Flow Cytometry, Immunoprecipitation, Paraffin Sections, Western blot / Immunoblot.

Properties for Ly6A/E / SCA1

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms Ly-6A.2/Ly-6E.1, Lymphocyte antigen 6A-2/6E-1, SCA-1, Stem cell antigen 1, T-cell-activating protein, TAP
Presentation Purified
Reactivity Ms
Applications F, IP, P, WB
Clonality Monoclonal
Clone D7
Host Rat
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P05533
Immunogen:
IL-2-dependent mouse T-cell line (CTL-L).
GeneID:
110454
Application FC
IHC
IP
WB
Background Ly-6A/E,;also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
Format
Purification:
The antibody was purified by affinity chromatography.
Buffer System:
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
State:
Purified

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