AM08056FC-N Ly6c antibody

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0.5 mg / €350.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rat anti Mouse Ly6c HK1.4


Product Description for Ly6c

Rat anti Mouse Ly6c HK1.4.
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for Ly6c

Product Category Primary Antibodies
Quantity 0.5 mg
Synonyms Ly-6C2, Ly6C2, Lymphocyte antigen 6C2, Mouse Macrophage Marker
Presentation FITC
Reactivity Ms
Applications F
Clonality Monoclonal
Clone HK1.4
Host Rat
Isotype IgG2c
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
Application Flow Cytometry: ≤ 1 µg/106 cells (Ref.1,2).
Background Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells, while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes. (Ref.1-4)
Concentration 0.5 mg/ml
General Readings
  1. Herold KC, Montag AG, Meyer SM, Wojcikowski C, Fitch FW. Expression of Ly-6C by T lymphocytes of NOD mice after CD3-complex stimulation. Identification of activated cells during insulitis of prediabetic mice. Diabetes. 1990 Jul;39(7):815-20. PubMed PMID: 2162302.
  2. Jutila MA, Kroese FG, Jutila KL, Stall AM, Fiering S, Herzenberg LA, et al. Ly-6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon-gamma. Eur J Immunol. 1988 Nov;18(11):1819-26. PubMed PMID: 2849552.
  3. Johnson R, Lancki DW, Fitch FW. Accessory molecules involved in antigen-mediated cytolysis and lymphokine production by cytotoxic T lymphocyte subsets. I. Identification of functions for the T cell surface molecules Ly-6C and Thy-1. J Immunol. 1993 Sep 15;151(6):2986-99. PubMed PMID: 8104217.
  4. Lancki DW, Fields P, Qian D, Fitch FW. Induction of lytic pathways in T cell clones derived from wild-type or protein tyrosine kinase Fyn mutant mice. Immunol Rev. 1995 Aug;146:117-44. PubMed PMID: 7493751.
Storage Store undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer.
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Fluorescein Isothiocyanate Isomer 1
Buffer System:
PBS containing 0.09% Sodium Azide as preservative.
Liquid purified Ig fraction.
This antibody is specific to Murine Ly-6C (Mr. 18 kDa)
Gene ID 100041546
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