NB100-64632 Lymphocytes antibody

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1 ml / €360.00
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Quick Overview

Mouse anti Guinea Pig Lymphocytes MsGp2

NB100-64632

Product Description for Lymphocytes

Mouse anti Guinea Pig Lymphocytes MsGp2.
Presentation: Supernatant
Product is tested for Frozen Sections, Paraffin Sections.

Properties for Lymphocytes

Product Category Primary Antibodies
Quantity 1 ml
Presentation Supernatant
Reactivity GP
Applications C, P
Clonality Monoclonal
Clone MsGp2
Host Mouse
Isotype IgG1
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Nylon wool adherent B cells
Application Immunohistochemistry-Frozen, Immunohistochemistry-Frozen, Immunohistochemistry-Frozen
Background Lymphocytes have receptors for antigen and confer specificity on an immune response. Lymphocytes express receptors with varying affinity for the antigen in question. Langerhans Cells are present in the skin and process efficiently antigen but cannot present it to T cells. Langerhans cells have been shown to pick up antigen in skin and carry it via afferent lymphatic vessels to lymph nodes. Recognises an antigen expressed by Langerhans cells, intermediate dendritic cells and interdigitating cells in T cell areas of rat lymphoid organs. Monocytes and macrophages in various organs and tissues are also stained.
Concentration 11.3 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Tissue culture supernatant
Buffer System:
0.09% Sodium Azide
Purity:
Tissue culture supernatant
State:
Supernatant
Specificity
Specificity:
NB100-64632 reacts with an antigen on the majority of T and B lymphocytes and thymocytes, although the antigen is not expressed by germinal centre cells of the lymph node (2). MSgp2 reacts strongly with epidermal Langerhans cells, giving a superior profile than anti-MHC Class II antibodies on these cells (1). MSgp2 has the same distribution as monoclonal antibody CT4 which detects an antigen reportedly involved in the organ non-specific trafficing of guinea pig lymphocytes (2). However, unlike CT4, MSgp2 does not functionally inhibit lymphocyte adherence to high endothelial venules in vitro (1).
Species:
Guinea Pig

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