discontinued

SM2192 Lymphozytes antibody

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2 ml / €440.00

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Mouse anti Guinea Pig Lymphozytes MsGp2

SM2192

Product Description for Lymphozytes

Mouse anti Guinea Pig Lymphozytes MsGp2.
Presentation: Supernatant
Product is tested for Frozen Sections.

Properties for Lymphozytes

Product Category Primary Antibodies
Quantity 2 ml
Presentation Supernatant
Reactivity GP
Applications C
Clonality Monoclonal
Clone MsGp2
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
Nylon wool adherent B cells.
Remarks:
Spleen cells from immunised BALB/c mice were fused with cells from the NS1 mouse myeloma cell line.
Application Immunohistochemistry on Frozen Sections.
Concentration 11.3 mg/ml
General Readings
  1. Healey DG, Baker D, Gschmeissner SE, Turk JL. An antigenic determinant common to lymphocytes and Langerhans cells of the guinea pig. Int Arch Allergy Appl Immunol. 1987;82(2):120-4. PubMed PMID: 2433227.
  2. Kraal G, Twisk A, Tan B, Scheper R. A surface molecule on guinea pig lymphocytes involved in adhesion and homing. Eur J Immunol. 1986 Dec;16(12):1515-9. PubMed PMID: 3816932.
  3. Baker D, Parker D, Healey DG, Turk JL. Induction of sensitization and tolerance in contact sensitivity with haptenated epidermal cells in the guinea-pig. Immunology. 1987 Dec;62(4):659-64. PubMed PMID: 2448230. (Free PMC Article available)
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Liquid Tissue Culture Supernatant containing 0.09% Sodium Azide
Supernatant
Specificity
Specificity:
This antibody reacts with an antigen on the majority of T and B lymphocytes and thymocytes, although the antigen is not expressed by germinal centre cells of the lymph node. MSgp2 reacts strongly with epidermal Langerhans cells, giving a superior profile than anti-MHC Class II antibodies on these cells.
MSgp2 has the same distribution as monoclonal antibody CT4 which detects an antigen reportedly involved in the organ non-specific trafficing of guinea pig lymphocytes. However, unlike CT4, MSgp2 does not functionally inhibit lymphocyte adherence to high endothelial venules in vitro.
Species:
Guinea Pig.

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