AP30526PU-N LZTR1 antibody

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Rabbit anti Human, Mouse, Rat LZTR1


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  • AP30526PU-N

Product Description for LZTR1

Rabbit anti Human, Mouse, Rat LZTR1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for LZTR1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Leucine zipper-like transcription regulator 1
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
LZTR1 antibody was raised against a 14 amino acid peptide near the amino terminus of human LZTR1.
Add. information Blocking peptide available: AP30526CP-N
Application ELISA.
Western blot: 1 - 2 μg/ml.
Immunohistochemistry on paraffin sections.
Background LZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
Concentration 1.0 mg/ml
General Readings
  1. Kurahashi H, Akagi K, Inazawa J, Ohta T, Niikawa N, Kayatani F, et al. Isolation and characterization of a novel gene deleted in DiGeorge syndrome. Hum Mol Genet. 1995 Apr;4(4):541-9. PubMed PMID: 7633402.
  2. Nacak TG, Leptien K, Fellner D, Augustin HG, Kroll J. The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis. J Biol Chem. 2006 Feb 24;281(8):5065-71. Epub 2005 Dec 15. PubMed PMID: 16356934.
Storage Store the antibody (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Peptide affinity chromatography
Buffer System:
PBS containing 0.02% sodium azide
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human, mouse, rat
Gene ID 8216

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