GTX11375 Macrophages / Neutrophils antibody

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100 Tests / €320.00

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Rat anti Human Macrophages / Neutrophils YTH 8.18


Product Description for Macrophages / Neutrophils

Rat anti Human Macrophages / Neutrophils YTH 8.18.
Presentation: Ig Fraction
Product is tested for Frozen Sections.

Properties for Macrophages / Neutrophils

Product Category Primary Antibodies
Quantity 100 Tests
Presentation Ig Fraction
Reactivity Hu
Applications C
Clonality Monoclonal
Clone YTH 8.18
Host Rat
Isotype IgG2b
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Human peripheral blood mononuclear cells.
Application IHC-Fr
Background Macrophages naturally phagocytose material in their surrounding without being activated. Certain microbial products, however, do activate these cells. The most potent of these activators is endotoxin, a component of the gram-negative bacterial cell wall. It is only after this activation process that the macrophage starts an inflammatory process, i.e. effective antigen presentation and cytokine secretion. Neutrophils are the most abundant leukocytes and the second most relevant Phagocytes, in the blood. These are the first cells to enter a tissue during infection. Neutrophils constitute the principal cells of acute inflammation.Their entrance is stimulated by chemotactic factors secreted from injured cells, resident tissue macrophages, and complement activation. Neutrophils can also be activated by Fc region of antibodies, and by T-cell derived cytokines. A very potent chemotactic factor for neutrophils is C5a, a peptide product of complement activation. Neutrophils contain abundant cytoplasmic granules, which contain toxic proteins. (clinical correlete:type III, roitt) They are short lived cells. They engulf microorganisms, destroy it, but die quickly thereafter. Neutrophils are activated by antibodies, complement and cytokines.
Concentration 2 mg/ml
Storage Keep as concentrated solution. Store at 4
IgG fraction
Buffer System:
Preservative: 0.09% Sodium Azide; Constituents: PBS. pH 7.4
IgG fraction
Ig Fraction
Human - Not yet tested in other species

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