AM00298PU-N MAGE-1 antibody

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Mouse anti Human MAGE-1 E22-11B2-E9


Product Description for MAGE-1

Mouse anti Human MAGE-1 E22-11B2-E9.
Presentation: Purified
Product is tested for Western blot / Immunoblot.

Properties for MAGE-1

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms DM3125, MAGE1
Presentation Purified
Reactivity Hu
Applications WB
Clonality Monoclonal
Clone E22-11B2-E9
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Full length recombinant human MAGE-1 protein.
AA Sequence:
Mol. Wt. of Antigen: 42-46 kDa
Isotype control AM03096PU-N
Application Western Blotting: Ab 1-2µg/ml for 2hrs at RT. Recommended positive control: Colo32 Cells.
Not suitable for Immunohistology.
Background Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, nonsmall cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
Concentration 0.2 mg/ml
General Readings
  1. van der Bruggen P et al. Science 1991;254(5038):1643-7.
Storage Store the antibody at 2 - 8 °C for one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Protein A chromatography
Buffer System:
10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide.
Liquid ascites fluid
This antibody detects MAGE-1.
Cellular Localization: Cytoplasmic.

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