NB120-5615 MAP2K1 antibody

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Rabbit anti Human, Mouse, Rat MAP2K1


Product Description for MAP2K1

Rabbit anti Human, Mouse, Rat MAP2K1.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for MAP2K1

Product Category Primary Antibodies
Quantity 0.05 ml
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Phosphopeptide derived from a region of human MEK 1 that contains threonine 386.
Concentration 0.5 mg/ml
General Readings General / background references:Sharma P et al. Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway. J Biol Chem 277:528-34 (2002). PubMed PMID: 11684694
Lin CC et al. Thrombin-stimulated cell proliferation mediated through activation of Ras/Raf/MEK/MAPK pathway in canine cultured tracheal smooth muscle cells. Cell Signal 14:265-75 (2002). PubMed PMID: 11812655
Jin K et al. MEK and ERK protect hypoxic cortical neurons via phosphorylation of Bad. J Neurochem 80:119-25 (2002). PubMed PMID: 11796750
Takahashi H et al. Expression of human cystatin A by keratinocytes is positively regulated via the Ras/MEKK1/MKK7/JNK signal transduction pathway but negatively regulated via the Ras/Raf-1/MEK1/ERK pathway. J Biol Chem 276:36632-8 (2001). PubMed PMID: 11451947
Xu B et al. The N-terminal ERK-binding site of MEK1 is required for efficient feedback phosphorylation by ERK2 in vitro and ERK activation in vivo. J Biol Chem 274:34029-35 (1999). PubMed PMID: 10567369
Immunogen affinity purified
Buffer System:
Preservative: 0.05% Sodium AzideConstituents: PBS, 1mg/ml BSA (IgG, protease free). pH 7.3
Immunogen affinity purified
Aff - Purified
Cross-reacts with Human, Mouse and Rat.Expected to cross-react with a wide range of other species (100% identity with immunogen) due to sequence homology.Not yet tested in other species.

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