AP00169PU-N MAP3K11 (C-term) antibody

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0.1 mg / €350.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse, Rat MAP3K11

Product Description for MAP3K11

Rabbit anti Human, Mouse, Rat MAP3K11.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot.

Properties for MAP3K11

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms MLK3, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, PTK1, Src-homology 3 domain-containing proline-rich kinase
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q16584
Immunogen:
Synthetic peptide mapping to the C-terminus of human MLK3.
GeneID:
4296
Property C-term
Application Western Blot: 0.5-4 μg/ml.
Background MLK3 (Mixed lineage kinase 3) is a serine/threonine kinase that has an amino-terminal SH3 domain followed by the kinase domain and two leucine zippers, a cdc42/Rac1 binding (CRIB) domain and several other domains/motifs at the carboxy-terminal region. MLK3 functions as a MAPKKK of the SAPK/JNK stress pathway by directly phosphorylating SEK1/MKK4 and MKK7, although it is controversial whether MLK3 is involved in p38 stress pathway activation. MLK3 also functions as an IκB kinase and mediates the activation of the transcriptional factor NF-κB stimulated by CD3/CD28, suggesting a role for MLK3 in immune and inflammatory responses.
Concentration 0.5 mg/ml
Storage Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity purified
Buffer System:
PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal
State:
Liquid
Aff - Purified
Specificity
Specificity:
The antibody recognizes 92 kDa MLK3. It does not cross react with MLK1, MLK2 and other mixed lineage kinases.
Species:
Human, Mouse, Rat.
Gene ID 4296

Accessory Products

Proteins and/or Positive Controls

Proteins for MAP3K11 (7 products)

Catalog No. Species Pres. Purity   Source  

MAP3K11

MAP3K11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

MAP3K11

MAP3K11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

MAP3K11

MAP3K11 Human Purified
  Abnova Taiwan Corp.

MAP3K11

MAP3K11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

MAP3K11

MAP3K11 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

MAP3K11

MAP3K11 Human
  Abnova Taiwan Corp.

MAP3K11

MAP3K11 Human
  Abnova Taiwan Corp.
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