AP00260PU-N MAPK8 / MAPK9 pThr183/pTyr185 antibody

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0.1 mg / €460.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse, Rat MAPK8 / MAPK9


Product Description for MAPK8 / MAPK9

Rabbit anti Human, Mouse, Rat MAPK8 / MAPK9.
Properties: pThr183/pTyr185
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Western blot / Immunoblot, Paraffin Sections.

Properties for MAPK8 / MAPK9

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms JNK-1, JNK-2, JNK-46, JNK-55, JNK1, JNK2, MAPK-8, MAPK-9, MAPK8, MAPK9, Mitogen-activated protein kinase 8/9, PRKM8, PRKM9, SAPK, Stress-activated protein kinase JNK11/JNK2, c-Jun N-terminal kinase 1/2
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications ICC/IF, IP, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Synthetic phospho-peptide corresponding to residues surrounding Thr183/Tyr185 of Human SAPK/JNK
Property pThr183/pTyr185
Application Western Blot: 1-2 µg/ml.
Immunoprecipitation: 10-20 µg/ml.
Immunocytochemistry: 10-20 µg/ml.
Immunohistochemistry: 20-30 µg/ml.
Background The JNK pathway is activated by largely distinct stimuli including inflammatory cytokines (such as TNF-alpha and IL-1), UV light, inhibitors of protein synthesis and osmotic stress. Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). JNK binds tightly to the N-terminal region of c-Jun and ATF-2, and phosphorylates c-Jun at Ser63 and Ser73 and ATF-2 at Thr69 and Thr71.
Concentration 0.5 mg/ml
Storage Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Affinity Chromatography.
Buffer System:
PBS, pH 7.2, containing 50% Glycerol, 1% BSA and 0.02% Sodium Azide
Liquid purified Ig fraction.
Aff - Purified
The antibody detects the p46 and p54 JNK/SAPK dually phosphorylated at Thr183 and Tyr185.
Human, Mouse and Rat.

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