NBP1-00910 MARK1/2/3/4 antibody

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Rabbit anti Human, Mouse, Rat MARK1/2/3/4


Product Description for MARK1/2/3/4

Rabbit anti Human, Mouse, Rat MARK1/2/3/4.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.

Properties for MARK1/2/3/4

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms MAP/Microtubule Affinity-Regulating Kinase, MARK
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications ICC/IF, P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Application ELISA, immunohistochemistry, Western Blot, This antibody is useful for the following applications and dilutions: ELISA 1:1000-1:5000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,, ELISA 1:1000-1:5000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200,
Background MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubulestability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.
Concentration 1 mg/ml
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Immunogen affinity purified
Buffer System:
15mM Sodium Azide
Immunogen affinity purified
Aff - Purified
MARK1/2/3/4 (N211) detects endogenous levels of MARK1/2/3/4 protein.
Human, Mouse, Rat

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