discontinued

NB100-2376 MCM2 antibody

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0.1 ml / €440.00

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Rabbit anti Human, Mouse MCM2

NB100-2376

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  • NB100-2376

Product Description for MCM2

Rabbit anti Human, Mouse MCM2.
Presentation: Aff - Purified
Product is tested for Frozen Sections.

Properties for MCM2

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Aff - Purified
Reactivity Hu, Ms
Applications C
Clonality Polyclonal
Host Rabbit
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Immunogen for NB 100-2376 was a synthetic phosphorylated peptide, which represented a portion of human Minichromosomal Maintenance Deficient 2 surrounding Serine 53 according to the numbering given in entry NP_004517.2 (GeneID 4171).
Background The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7
Format
Purification:
Affinity purified
Buffer System:
Tris-buffered Saline containing 0.1% BSA
Purity:
Affinity purified
State:
Aff - Purified
Specificity
Species:
Human and mouse. Other species have not been tested.

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