discontinued

ARP36645_P050 MCM3 antibody

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Rabbit anti Bovine, Canine, Human, Mouse, Rat MCM3

ARP36645_P050

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  • ARP36645_P050

Product Description for MCM3

Rabbit anti Bovine, Canine, Human, Mouse, Rat MCM3.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for MCM3

Product Category Primary Antibodies
Target Category
Quantity 50 µg
Synonyms DNA polymerase alpha holoenzyme-associated protein P1, DNA replication licensing factor MCM3, P1-MCM3, P102 protein, RLF subunit beta, mini-chromosome maintenance protein 3
Presentation Aff - Purified
Reactivity Bov, Can, Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer AVIVA Systems Biology

Datasheet Extract

Immunogen
Swiss Prot Num:
P25205
Immunogen:
Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human MCM3 with an internal ID of S06307
GeneID:
4172
Add. information Rabbit Ig G is purified by peptide affinity chromatography method. 89kDa
Application Suggested dilution at 0.25 ELISA titre using peptide based assay: 1:12500
Background MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
General Readings Shukla,A., (2005) Biochem. Biophys. Res. Commun. 329 (4), 1240-1245
Storage Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
Format
Purification:
Rabbit Ig G is purified by peptide affinity chromatography method.
Buffer System:
Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles.
State:
Aff - Purified
Specificity
Species:
Human
Gene ID 4172

Accessory Products

Proteins and/or Positive Controls

Proteins for MCM3 (3 products)

Catalog No. Species Pres. Purity   Source  

MCM3

MCM3 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

MCM3

MCM3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

MCM3

MCM3 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

Positive controls for MCM3 (2 products)

Catalog No. Species Pres. Purity   Source  

MCM3 Lysate

Western Blot: MCM3 Lysate [NBL1-12951] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for MCM3
  Novus Biologicals Inc.

MCM3 overexpression lysate

MCM3 overexpression lysate
0.1 mg / €280.00
  OriGene Technologies, Inc.
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