TA322369 MDC1 antibody

Anti-MDC1 Rabbit Polyclonal Antibody

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0.1 ml / €335.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human, Mouse, Rat MDC1

Product Description for MDC1

Rabbit anti Human, Mouse, Rat MDC1.
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections.

Properties for MDC1

Product Category Primary Antibodies
Target Category
Quantity 0.1 ml
Synonyms KIAA0170, MDC1, Mediator of DNA damage checkpoint protein 1, NFBD1
Presentation Purified
Reactivity Hu, Ms, Rt
Applications E, P
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Swiss Prot Num:
Synthetic peptide corresponding to a region derived from 1866-1881 amino acids of Human mediator of DNA-damage checkpoint 1.
Application ELISA: 1:2000-10000
IHC: 1:100-300
Background The protein encoded by this gene contains an N-termil forkhead domain; two BRCA1 C-termil (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to D damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of D double-strand breaks through its BRCT motifs; and facilitates recruitment of the ATM kise and meiotic recombition 11 protein complex to D damage foci.
Antigen affinity purification
Buffer System:
PBS pH7.3, 0.05% NaN3, 50% glycerol.

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