AP55964PU-N Megf10 (Cytoplasm. Dom) antibody

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Rabbit anti Mouse Megf10


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  • AP55964PU-N

Product Description for Megf10

Rabbit anti Mouse Megf10.
Properties: (Cytoplasm. Dom)
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for Megf10

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Multiple EGF-like domains protein 10, Multiple epidermal growth factor-like domains protein 10
Presentation Aff - Purified
Reactivity Ms
Applications ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Swiss Prot Num:
Histidine-tagged recombinant protein corresponding to the cytoplasmic domain of mouse Megf10.
Property Cytoplasm. Dom
Application Immunofluorescence: A representative lot was used by an independent laboratory in P7 caudal brain tissue and retina cells. Image courtesy from the laboratory of Dr. Joshua Sanes, Harvard University.
Western Blot: 1 µg/mL of this antibody detected Megf10 on 10 µg of mouse retina tissue lysate.
Background Multiple epidermal growth factor-like domains protein 10 (Megf10) is a type 1 transmembrane protein with multiple EGF-like extracellular domains. Megf10 is highly expressed in the brain, and plays an important role in phacocytosis of apoptotic cells. This role may be performed through the interaction of Megf10 with the ATP-binding cassette transporter (ABCA1) protein. Previous studies have suggested that Megf10 may be involved in the uptake of amyloid β peptides in the brain. Megf10 may therefore play a role Alzheimer’s disease.
Concentration lot-specific
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
Affinityn Chromatography
Buffer System:
0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Liquid purified Ig fraction
Aff - Purified
This antibody recognizes Megf10 at the cytoplasmic domain.
Demonstrated to react with Mouse. Other homologies: Rat (98% sequence homology) and Human (92% sequence homology).

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