AM10111SU-N Melanocytes antibody

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Mouse anti Human Melanocytes PNL2

Product Description for Melanocytes

Mouse anti Human Melanocytes PNL2.
Presentation: Supernatant
Product is tested for Western blot / Immunoblot, Immunoprecipitation, Frozen Sections, Paraffin Sections.

Properties for Melanocytes

Product Category Primary Antibodies
Quantity 1 ml
Presentation Supernatant
Reactivity Hu
Applications C, IP, P, WB
Clonality Monoclonal
Clone PNL2
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Application Western blot. 
Immunohistochemistry on Frozen sections.
Immunohistochemistry on Paraffin sections.
Typical Starting Working Dilution: 1/10.
Background Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre existing benign nevus, which occurs most often in the skin but also may involve other sites.
General Readings
  1. Rochaix P, Lacroix-Triki M, Lamant L, Pichereaux C, Valmary S, Puente E, et al. PNL2, a new monoclonal antibody directed against a fixative-resistant melanocyte antigen. Mod Pathol. 2003 May;16(5):481-90. PubMed PMID: 12748255.
Storage Store undiluted at 2-8°C.
Shelf life: one year from despatch.
0.02% Sodium azide
Liquid culture medium
Species Reactivity
Species reactivity (tested):
The monoclonal antibody clone PNL2 recognizes a melanocyte associated antigen. The antigen recognised by PNL2 is chemically resistant and thus allows immunostaining after bleaching or decalcification.
PNL2 stains only melanocytic lesions, clear cell sarcoma, melanotic schwannome, angiomyolipoma and lymphangioleiomyomatosis. PNL2 has the same specificity as anti Melan-A and HMB-45 antibodies. However PNL2 staining is stronger and more consistent.
The antigen recognized by PNL2 is different from Melan-A and gp100.

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