AM32147SU-N Melanoma Discriminated Antigen antibody

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1 ml / €260.00
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Quick Overview

Mouse anti Human Melanoma Discriminated Antigen PAL-M2


Product Description for Melanoma Discriminated Antigen

Mouse anti Human Melanoma Discriminated Antigen PAL-M2.
Presentation: Supernatant
Product is tested for Frozen Sections.

Properties for Melanoma Discriminated Antigen

Product Category Primary Antibodies
Quantity 1 ml
Presentation Supernatant
Reactivity Hu
Applications C
Clonality Monoclonal
Clone PAL-M2
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isolated from Human Melanoma cells.
Application Immunohistochemistry on Frozen Sections: Use at 1/5-1/25 preferably in PBS.
Melanoma is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the rarer types of skin cancer but causes the majority of skin cancer related deaths. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a thickness of greater than 1 mm.
General Readings
  1. Ruiter, D.J. et al., 1985, J. Invest. Dermatol., 85, 2.

Store undiluted  (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

10mM Sodium Azide
Species Reactivity
Species reactivity (tested):
Detects Melanoma Discriminated Antigen in Human samples.
This Monoclonal antibody clone PAL-M2 stains a minority of primary melanomas and half of the metastatic lesions tested. It rarely stains dysplastic naevi or common cellular naevi using standard immunohistochemical conditions. The antibody recognizes two protein bands in Immunoblotting with a Molecular Weight of 95-100 kD. 
 Cross reactivity:
Skin carcinomas:  not detectable
Dendritic cells in inflammatory infiltrates: present 
Sebaceous glands  : present
Non-cutaneous tumors: present

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