AP05773PU-N mGluR2/3 antibody

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Rabbit anti Bovine, Canine, Human, Monkey, Mouse, Rat, Zebrafish mGluR2/3


Product Description for mGluR2/3

Rabbit anti Bovine, Canine, Human, Monkey, Mouse, Rat, Zebrafish mGluR2/3.
Presentation: Purified
Product is tested for Frozen Sections, Western blot / Immunoblot.

Properties for mGluR2/3

Product Category Primary Antibodies
Quantity 0.1 ml
Presentation Purified
Reactivity Bov, Can, Hu, Mky, Ms, Rt, Ze
Applications C, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Peptide from the C-terminal region of rat mGluR2 and rat mGluR3.
Application Immunohistochemistry on frozen sections: 1:500.
Western Blot: 1:1000; detects bands of approximately 110kDa (monomer) and 220kDa (dimer) in rat hippocampal lysates.
Background The metabotropic glutamate receptors have been organised into three groups, mGluR2 and mGluR3 make up group II, and are negatively coupled to adenylate cyclase. Group II mGluRs act to inhibit neurotransmitter release as autoreceptors on glutamatergic terminals and as presynaptic heteroreceptors, performing a variety of functions in the central and peripheral nervous system. Studies have shown that mGluRs play an important role in neuroplasticity and group II mGluRs are targeted by various drugs used for treating anxiety, Parkinson’s disease, schizophrenia and drug addiction.
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage Store at +4°C or at -20°C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. 18 months from date of despatch.
Buffer System:
200mM Tris-Glycine pH7.5 containing 0.09% Sodium Azide (NaN3)
Liquid purified IgG
This antibody recognises rat metabotropic glutamate receptor 2 and 3 (mGluR2 and mGluR3).

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