GTX10307 mGluR2/3 antibody

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0.1 ml / €380.00

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Rabbit anti Human, Mouse, Rat mGluR2/3


Product Description for mGluR2/3

Rabbit anti Human, Mouse, Rat mGluR2/3.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.

Properties for mGluR2/3

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms GRM2, GRM3, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 2/3, Metabotropic glutamate receptor 3, mGlu 2, mGlu 3, mGlu2
Presentation Aff - Purified
Reactivity Hu, Ms, Rt
Applications C, ICC/IF, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Synthetic peptide: NGREVVDSTTSSL corresponding to the c-terminus region (Rat).
Application ICC, IHC-Fr, WB
Background L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Storage Keep as concentrated solution. Store at 4
Immunogen affinity purified
Buffer System:
Preservative: 0.1% Sodium Azide; Constituents: 1.0% BSA, Tris-glycine. pH 7.8
Immunogen affinity purified
Aff - Purified
Cross-reacts with Rat. Expected to cross-react with Human (100% identity with immunogen) and Mouse (92% identity with immunogen) due to sequence homology. Not yet tested in other species.

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