discontinued

GTX30187 mGluR2/3 antibody

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0.1 ml / €440.00

Quick Overview

Rabbit anti Rat mGluR2/3

GTX30187

Product Description for mGluR2/3

Rabbit anti Rat mGluR2/3.
Presentation: Aff - Purified
Product is tested for Frozen Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for mGluR2/3

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms GRM2, GRM3, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 2/3, Metabotropic glutamate receptor 3, mGlu 2, mGlu 3, mGlu2
Presentation Aff - Purified
Reactivity Rt
Applications C, IP, WB
Clonality Polyclonal
Host Rabbit
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer GeneTex Inc.

Datasheet Extract

Immunogen
Immunogen:
This antibody was raised against a synthetic peptide corresponding to the 13 c-terminus amino acids of mGluR2/3 with an N-appended lysine coupled to thyroglobulin using glutaraldehyde.
Application IHC-Fr, IP, WB
Background Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainate receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors, stimulate phospholipase C as revealed by an increase in phosphoinositide turnover, and Ca2+ release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3.
Concentration 0.113 mg/ml
Storage Keep as concentrated solution. Store at 4
Format
Purification:
Affinity purified
Buffer System:
Tris - glycine, 0.1% sodium azide
Purity:
Affinity purified
State:
Liquid
Aff - Purified
Specificity
Specificity:
Rat mGluR2/3 - Other species have not been tested, but should work with most mammalian species due to sequence homology. Not yet tested in other species

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