discontinued

NB120-15302 mGluR2/3 antibody

See related secondary antibodies

Search for all "mGluR2/3"

7 ml / €360.00

Quick Overview

Rabbit anti Birds, Human, Monkey, Mouse, Rat mGluR2/3

Product Description for mGluR2/3

Rabbit anti Birds, Human, Monkey, Mouse, Rat mGluR2/3.
Product is tested for Paraffin Sections.

Properties for mGluR2/3

Product Category Primary Antibodies
Quantity 7 ml
Synonyms GRM2, GRM3, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 2/3, Metabotropic glutamate receptor 3, mGlu 2, mGlu 3, mGlu2
Reactivity Av, Hu, Mky, Ms, Rt
Applications P
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Immunogen:
Synthetic peptide (Human) (C terminal).
Add. information Research Areas: Cancer, Neuroscience
Application Immunohistochemistry-Paraffin, IHC-P: ready-to-use for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate, pH 6.0 for 10 min followed by cooling at RT for 20 min.Not tested in other applications., Immunohistochemistry-Paraffin
Background L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Affinity purified
Buffer System:
Sodium Azide
Purity:
Affinity purified
Specificity
Specificity:
metabotropic Glutamate Receptor 2/3
Species:
Avian, Human, Mouse, Primate, Rat
FocusOn and Reviews
FocusOns:

Accessory Products

  • LinkedIn