AP05774PU-N mGluR5/1 antibody

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Rabbit anti Human, Mouse, Rat mGluR5/1


Product Description for mGluR5/1

Rabbit anti Human, Mouse, Rat mGluR5/1.
Presentation: Purified
Product is tested for Frozen Sections, Western blot / Immunoblot.

Properties for mGluR5/1

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms GPRC1E, GRM5, MGLUR5A, MGLUR5B, Metabotropic glutamate receptor 5/1
Presentation Purified
Reactivity Hu, Ms, Rt
Applications C, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Peptide from the C-terminal region of rat mGluR5 and rat mGluR1a.
Application Immunohistochemistry on frozen sections: 1:500.
Western Blot: 1:1000; detects bands of approximately 125kDa (monomer) and 250kDa (dimer) in HEK293 cells.
Background The metabotropic glutamate receptors have been organised into three groups, mGluR5 and mGluR1 make up group I which, when activated, stimulates phospholipase C and activates protein kinase C to hydrolyse phosphoinositide phospholipids in the cell membrane. Group I mGluRs, but not other groups, are activated by 3, 5-dihydroxyphenylglycine (DHPG).
Caution (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
200mM Tris-Glycine pH7.5 containing 0.09% Sodium Azide (NaN3)
Liquid purified IgG
This antibody recognises rat metabotropic glutamate receptor 5 and 1a (mGluR5 and mGluR1a).
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