AM26368PU-N MGO-modified proteins antibody

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0.1 mg / €390.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

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Mouse anti var. MGO-modified proteins MGO-1

AM26368PU-N

Product Description for MGO-modified proteins

Mouse anti var. MGO-modified proteins MGO-1.
Presentation: Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections, Enzyme Immunoassay.

Properties for MGO-modified proteins

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation Purified
Reactivity var.
Applications E, P, WB
Clonality Monoclonal
Clone MGO-1
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Immunogen:
MGO-modified KLH
Isotype control AM03095PU-N
Application Immunoassays.
Immunohistochemistry on paraffin sections: The typical starting working dilution is 1:50.
Western blot.
Background Methylglyoxal (MGO) is an endogenous product of glucose metabolism. Increased production and accumulation of methylglyoxal (MGO), as well as increased modification of proteins by glycoxidation, are hallmarks of aging and diabetes. MGO was shown to modify proteins and to contribute to the accumulation of damaged proteins that can be toxic to cells. A number of studies have shown that MGO levels are significantly elevated in patients with Type 2 Diabetes  and correlates well with fasting plasma glucose and hemoglobin A1c (HbA1c) levels. Moreover, increased formation of the MGO is implicated in renal dysfunction and is known to be involved in the development of DN (diabetic nephropathy).
Concentration 0.1 mg/ml
Storage Store at 2 - 8 °C.
Shelf life: one year from despatch.
Format
Purification:
Protein G
Buffer System:
PBS
Preservatives:
0.02% sodium azide
Stabilizers:
0.1% bovine serum albumin
State:
Liquid 0.2 µm filtered Ig fraction
Purified
Species Reactivity
Species reactivity (tested):
Human. Multispecies cross reactant.
Specificity
Specificity:
The monoclonal antibody MGO-1 recognizes human MGO modified proteins.

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