discontinued

bs-2387R MHC class I antibody

See related secondary antibodies

Search for all "MHC class I"

0.1 ml / €230.00

Quick Overview

Rabbit anti Human MHC class I

bs-2387R

Product Description for MHC class I

Rabbit anti Human MHC class I.
Presentation: Purified
Product is tested for Paraffin Sections.

Properties for MHC class I

Product Category Primary Antibodies
Quantity 0.1 ml
Synonyms HLA Class 1, MHC Class 1
Presentation Purified
Reactivity Hu
Applications P
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe only
PDF datasheet View Datasheet
Manufacturer Bioss, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q96QC4
Immunogen:
KLH conjugated synthetic peptide derived from human MHC class I.
GeneID:
100507436
Background HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described. [provided by RefSeq, Jul 2008]
Storage Store at -20°C for 12 months.
Format
Purification:
Purified by Protein A and peptide affinity chromatography.
Buffer System:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.
State:
Purified

Accessory Products

Proteins and/or Positive Controls

Proteins for MHC class I (1 products)

Catalog No. Species Pres. Purity   Source  

MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801).

MHC class I polypeptide-related sequence A (MICA), transcript variant 1 (allele MICA*00801). Human > 80 %
Preparation: or Add: Recombint proteins was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.
  • LinkedIn