BM2237F MHC Class I H-2Kd/Dd,q,u,v antibody

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Mouse anti Mouse MHC Class I H-2Kd/Dd,q,u,v B3A6-Do7


Product Description for MHC Class I H-2Kd/Dd,q,u,v

Mouse anti Mouse MHC Class I H-2Kd/Dd,q,u,v B3A6-Do7.
Presentation: FITC
Product is tested for Immunocytochemistry/Immunofluorescence, Flow Cytometry.

Properties for MHC Class I H-2Kd/Dd,q,u,v

Product Category Primary Antibodies
Quantity 0.5 mg
Presentation FITC
Reactivity Ms
Applications F, ICC/IF
Clonality Monoclonal
Clone B3A6-Do7
Host Mouse
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Isotype control SM12F
Application FACS analysis: Use 1 µg to stain 1x10e6 cells in Flow Cytometry.
Haplotype identification.
Complement-dependent cytotoxicity.
Western blotting.
Heterozygote typing.
Background MHC Class I H2 Kd is involved in the presentation of foreign antigens to the immune system. The ''classical'' MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant Beta2-microglobulin. These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny.
Concentration 0.5 mg/ml
General Readings
  1. Hauptfeld, V. (1984) Immunogenetics 19: 169.
Storage Store the antibody undiluted at 2-8°C.
This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Protein G Chromatography
Buffer System:
0.01 M PBS pH 7.2 with 0.09% Sodium Azide as a preservative and 1% BSA as stabilizer.
Liquid purified Ig fraction.
Antibody recognizes classical class I antigen, detecting a public specificity shared by both loci K and D.
Classical class I antigen, ubiquitously expressed.
Antigen is present on 100% of T-Cells, B-Cells, Erythrocytes, Macrophages, endocrine Cells, Endothelial and Epithelial Cells.

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