SM2081F MHC Class II DQ/DR (polymorphic) antibody

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0.1 mg / €440.00
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Quick Overview

Mouse anti Sheep MHC Class II DQ/DR 49.1

Product Description for MHC Class II DQ/DR

Mouse anti Sheep MHC Class II DQ/DR 49.1.
Properties: (polymorphic)
Presentation: FITC
Product is tested for Flow Cytometry.

Properties for MHC Class II DQ/DR

Product Category Primary Antibodies
Quantity 0.1 mg
Presentation FITC
Reactivity Sh
Applications F
Clonality Monoclonal
Clone 49.1
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Property polymorphic
Application Flow Cytometry: 1/10; Use 10µl of the suggested working dilution to label 1 x 10e6 cells in 100µl.
Background The expression of ovine MHC class II molecules is restricted to B cells, activated T cells, monocytes, macrophages, dendritic cells and some endothelial and epithelial cells.
Concentration 0.1 mg/ml
General Readings
  1. Puri NK, Gogolin-Ewens KJ, Brandon MR. Monoclonal antibodies to sheep MHC class I and class II molecules: biochemical characterization of three class I gene products and four distinct subpopulations of class II molecules. Vet Immunol Immunopathol. 1987 May;15(1-2):59-86. PubMed PMID: 3303652.
  2. Puri NK, Brandon MR. Sheep MHC class II molecules. II. Identification and characterization of four distinct subsets of sheep MHC class II molecules. Immunology. 1987 Dec;62(4):575-80. PubMed PMID: 3480873. (Free PMC Article available)
  3. Puri NK, de Kretser T, Brandon MR. Monoclonal antibodies to sheep MHC class II molecules recognize all HLA-D or subsets of HLA-D region products. Hum Immunol. 1987 Nov;20(3):195-207. PubMed PMID: 3501780.
  4. Ballingall KT, Dutia BM, Hopkins J, Wright H. Analysis of the fine specificities of sheep major histocompatibility complex class II-specific monoclonal antibodies using mouse L-cell transfectants. Anim Genet. 1995 Apr;26(2):79-84. PubMed PMID: 7733511.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.
Format
Label:
Fluorescein Isothiocyanate Isomer 1
FITC
Purification:
Affinity chromatography on Protein G
Buffer System:
PBS, pH 7.4 containing 0.09% Sodium Azide and 1% Bovine Serum Albumin
State:
Liquid purified IgG
Specificity
Specificity:
This antibody recognises a polymorphic epitope on MHC class II DQ and DR molecules. In recent work, this clone was found to recognise MHC class II transfectants DQ - T28.1. DR - T8.1. DR - T31.3, but not DQ - T26.2 (Ballingall, K. et al. 1995)
Species:
Sheep, Bovine, Goat, Human.

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