SM611 MHC Class II DQ (Ia) antibody

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Mouse anti Rabbit MHC Class II DQ (Ia) 2C4


Product Description for MHC Class II DQ (Ia)

Mouse anti Rabbit MHC Class II DQ (Ia) 2C4.
Presentation: Supernatant
Product is tested for Frozen Sections, Immunoprecipitation, Flow Cytometry.

Properties for MHC Class II DQ (Ia)

Product Category Primary Antibodies
Quantity 2 ml
Presentation Supernatant
Reactivity Rb
Applications C, F, IP
Clonality Monoclonal
Clone 2C4
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Rabbit Spleen Cells. Spleen cells from immunised mice were fused with cells of the P3.X63. Ag8.653 mouse myeloma cell line.
Application Flow Cytometry (Neat)
Immunohistochemistry on Frozen Sections.
Concentration 17.5 mg/ml
General Readings
  1. Lobel SA, Knight KL. The role of rabbit Ia molecules in immune functions as determined with the use of an anti-Ia monoclonal antibody. Immunology. 1984 Jan;51(1):35-43. PubMed PMID: 6197360. (Free PMC Article available)
  2. Spicker-Polet, H. et al. (1990) Rabbit Major Histocompatibility Complex IV. Expression of Major Histocompatability Complex Class II Genes. J. Immunogenetics 17: 123-132.
  3. Matsumura T, Kugiyama K, Sugiyama S, Ota Y, Doi H, Ogata N, et al. Suppression of atherosclerotic development in Watanabe heritable hyperlipidemic rabbits treated with an oral antiallergic drug, tranilast. Circulation. 1999 Feb 23;99(7):919-24. PubMed PMID: 10027816.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Buffer System:
Containing 0.2M Tris/HCl pH7.4 and 5-10% Foetal Calf Serum and 0.09% Sodium Azide
Liquid Tissue Culture Supernatant
This antibody recognises the class II RLA-DQ molecule. It inhibits the mixed lymphocyte reaction by 80%.
Immunoprecipitation studies yield three bands of molecular weight 28, 31 and 35kD.

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