NB100-65420 MHC Class II DQ antibody

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Mouse anti Rabbit MHC Class II DQ 2C4


Product Description for MHC Class II DQ

Mouse anti Rabbit MHC Class II DQ 2C4.
Presentation: Supernatant
Product is tested for Frozen Sections, Flow Cytometry, Immunoprecipitation, Paraffin Sections.

Properties for MHC Class II DQ

Product Category Primary Antibodies
Quantity 1 ml
Presentation Supernatant
Reactivity Rb
Applications C, F, IP, P
Clonality Monoclonal
Clone 2C4
Host Mouse
Isotype IgG2a
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Rabbit Spleen Cells
Add. information Research Areas: Immunology
Application flow cytometry / FACS analysis, Immunohistochemistry-Frozen, immunoprecipitation, Immunohistochemistry-Frozen, Immunoprecipitation and Flow cytometry / FACS analysis, Immunohistochemistry-Frozen immunoprecipitation flow cytometry / FACS analysis
Background MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Tissue culture supernatant
Buffer System:
0.09% Sodium Azide
Tissue culture supernatant
Recognizes the class II RLA-DQ molecule. It inhibits the mixed lymphocyte reaction by 80%. Immunoprecipitation studies yield three bands of molecular weight 28, 31 and 35kD.

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