SM495 MHC Class II DQ antibody

See related secondary antibodies

Search for all "MHC Class II DQ"

Quick Overview

Mouse anti Bovine, Porcine MHC Class II DQ K274.3G8


Product Description for MHC Class II DQ

Mouse anti Bovine, Porcine MHC Class II DQ K274.3G8.
Presentation: Supernatant
Product is tested for Frozen Sections, Flow Cytometry, Paraffin Sections.

Properties for MHC Class II DQ

Product Category Primary Antibodies
Quantity 2 ml
Presentation Supernatant
Reactivity Bov, Por
Applications C, F, P
Clonality Monoclonal
Clone K274.3G8
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Porcine peripheral blood lymphocytes.
Spleen cells from immunised mouse were fused with cells of the P3-X63-Ag.653 myeloma cell line.
Application Immunohistochemistry on Frozen Sections: 1/5-1/30.
Immunohistochemistry on Paraffin Sections: 1/5-1/30.
Flow Cytometry: 1/5-1/30. Use 50µl of the suggested working dilution to label 1 x 106 peripheral blood lymphocytes in 100µl.
Background The Major Histocompatibility Complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the Swine Leukocyte Antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR.
General Readings 1. Lunney, J.K. (1993) Characterisation of swine leucocyte differentiation antigens. Immunology Today 14: 147.
2. Brodersen R, Bijlsma F, Gori K, Jensen KT, Chen W, Dominguez J, et al. Analysis of the immunological cross reactivities of 213 well characterized monoclonal antibodies with specificities against various leucocyte surface antigens of human and 11 animal species. Vet Immunol Immunopathol. 1998 Jun 30;64(1):1-13. PubMed PMID: 9656427.
3. Sarradell J, Andrada M, Ramírez AS, Fernández A, Gómez-Villamandos JC, Jover A, et al. A morphologic and immunohistochemical study of the bronchus-associated lymphoid tissue of pigs naturally infected with Mycoplasma hyopneumoniae. Vet Pathol. 2003 Jul;40(4):395-404. PubMed PMID: 12824511.
4. Inman, C.F. et al. (2010) Dendritic cells interact with CD4 T cells in intestinal mucosa.
J Leukoc Biol. Jun 15. [Epub ahead of print]

5. Faure, J.P. et al. (2002) Polyethylene glycol reduces early and long-term cold ischemia-reperfusion and renal medulla injury.
J Pharmacol Exp Ther. 302: 861-70.

6. Hauet, T. et al. (2002) Polyethylene glycol reduces the inflammatory injury due to cold ischemia/reperfusion in autotransplanted pig kidneys.
Kidney Int. 62: 654-67.
7. Paillot, R. et al. (2001) Functional and phenotypic characterization of distinct porcine dendritic cells derived from peripheral blood monocytes.
Immunology. 102: 396-404.

8. Yang, P. et al. (2002) Immune cells in the porcine retina: distribution, characterization and morphological features.
Invest Ophthalmol Vis Sci. 43: 1488-92.

9. Jayle, C. et al. (2007) Comparison of protective effects of trimetazidine against experimental warm ischemia of different durations: early and long-term effects in a pig kidney model.
Am J Physiol Renal Physiol. 292: F1082-93.

10. Park, J.Y. et al. (2008) Characterization of interaction between porcine reproductive and respiratory syndrome virus and porcine dendritic cells.
J Microbiol Biotechnol. 18: 1709-16.

11. Maasilta, P.K. et al. (2005) Immune cells in a heterotopic lamb-to-pig bronchial xenograft model.
Transpl Int. 18: 1100-8.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
0.09% Sodium Azide
5-10% foetal calf serum
Liquid Tissue Culture Supernatant
Species Reactivity
Species reactivity (tested):
Pig.Cross reacts with Bovine.
Clone K274.3G8 recognizes SLA DQ molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells.

Accessory Products

  • LinkedIn