AM08075RP-N MHC Class II I-Ab antibody

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0.2 mg / €400.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Rat anti Mouse MHC Class II I-Ab NIMR-4

AM08075RP-N

Product Description for MHC Class II I-Ab

Rat anti Mouse MHC Class II I-Ab NIMR-4.
Presentation: PE
Product is tested for Flow Cytometry.

Properties for MHC Class II I-Ab

Product Category Primary Antibodies
Target Category
Quantity 0.2 mg
Synonyms H-2 class II histocompatibility antigen I-A beta chain, H2-Eb1
Presentation PE
Reactivity Ms
Applications F
Clonality Monoclonal
Clone NIMR-4
Host Rat
Isotype IgG2b
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P18468
Isotype control SM19R
Application Flow Cytometry: < / = 0.1 µg/10e6 cells.
Background MHC Class II antigens are heterodimers consisting of one alpha chain(31-34kD) and one beta chain (26-29kD). The family of monoclonal antibodies (ER-TR 3, ER-TR 2, ER-TR 1) detect MHC class II antigens encoded by the murine Ia region of the H-2 complex, corresponding to the human HLA-DR region. MHC Class II antigens are a valuable tool for studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus. MHC Class II antigens are also inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma.
Concentration 0.1 mg/ml
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
R-Phycoerythrin
PE
Buffer System:
PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
State:
Liquid purified Ig fraction.
Specificity
Specificity:
Specific to MHC Class II molecules.
This antibody reacts specifically with a non-polymorphic I-A-encoded epitope on MHC Class II antigens. Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells.
Species:
Mouse.

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