AM08076RP-N MHC Class II I-Ab antibody

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0.1 mg / €320.00
Please visit the country specific website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Mouse anti Mouse MHC Class II I-Ab 25-9-3

AM08076RP-N

Product Description for MHC Class II I-Ab

Mouse anti Mouse MHC Class II I-Ab 25-9-3.
Presentation: PE
Product is tested for Flow Cytometry.

Properties for MHC Class II I-Ab

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms H-2 class II histocompatibility antigen I-A beta chain, H2-Eb1
Presentation PE
Reactivity Ms
Applications F
Clonality Monoclonal
Clone 25-9-3
Host Mouse
Isotype IgM
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Monoclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
P18468
Immunogen:
C3H.SW splenocytes. (Ref.1)
Application Flow Cytometry: < / = 0.2 µg/10e6 cells.
Background MHC Class II antigens are involved in antigen presentation by Antigen Presenting Cells (APCs) to CD4+ T cells. They are constitutively expressed on APCs including B cells, macrophages, monocytes and dendritic cells, and are inducible on a number of other cells (endothelium and epithelial cells) by interferon gamma. The Mouse H2 Ab locus is orthologous to human DQB, which varies from typical class II genes in that both the alpha and beta chains are polymorphic.
Concentration 0.1 mg/ml
General Readings
  1. Ozato, K., and D.H. Sachs. 1981. J. Immunol. 126:317-321.
Storage Store the antibody undiluted at 2-8°C.
DO NOT FREEZE!
This product is photosensitive and should be protected from light.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Label:
R-Phycoerythrin
PE
Buffer System:
PBS containing 0.09% Sodium Azide as preservative and a stabilizing agent.
State:
Liquid purified Ig fraction.
Specificity
Specificity:
This antibody reacts specifically with the I-Ab haplotype of MHC Class II molecules.
Class II antigens are predominantly expressed on antigen-presenting cells including B lymphocytes, macrophages, dendritic cells and certain epithelial cells.
Species:
Mouse.

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