NB100-77549 MHC Class II (I-Ak) antibody

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0.5 mg / €780.00
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Quick Overview

Mouse anti Mouse MHC Class II (I-Ak) 11-5.2

Product Description for MHC Class II (I-Ak)

Mouse anti Mouse MHC Class II (I-Ak) 11-5.2.
Presentation: Biotin
Product is tested for Flow Cytometry.

Properties for MHC Class II (I-Ak)

Product Category Primary Antibodies
Quantity 0.5 mg
Presentation Biotin
Reactivity Ms
Applications F
Clonality Monoclonal
Clone 11-5.2
Host Mouse
Isotype IgG2b
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

CKB mouse splenocytes
Application flow cytometry / FACS analysis, flow cytometry / FACS analysis For immunofluorescent staining, the suggested use of this reagent is: 0.25 microgram per one millioncells in 100 microliter volume. , flow cytometry / FACS analysis
Background The 11-5.2 antibody reacts with the alpha chain of the I-Ak MHC class II alloantigen. These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2k bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins. The 11-5.2 antibody cross-reacts with cells from mice bearing the H-2r haplotype. Reactivity with other H-2 haplotypes (e.g., b, d, f, p, q, s) has not been observed. The 11-5.2 antibody has been reported to block antigen presentation and induce B cell differentiation.
General Readings
  1. Watts, C. 1997. Ann. Rev. Immunol. 15:821. 2. Pamer, E., et al., 1998. Ann. Rev. Immunol. 16:323.
Storage Store at 4C. Do not freeze.
Immunogen affinity purified
Buffer System:
0.09% Sodium Azide
Immunogen affinity purified
I-Ak (11-5.2)

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